A new large-scale DNA study of more than 3,200 Japanese people is challenging the long-held view that Japan’s ancestry comes mainly from two ancient sources. Using whole-genome sequencing across seven regions, researchers found evidence for a third ancestral group tied to northeastern Asia, with patterns that vary sharply by geography. The work also shows Japan is more genetically diverse than assumed, and pairs genomic data with medical records to build JEWEL for future personalized medicine.
A new genome reference set built around India’s diverse ethnic groups could improve cancer modelling and treatment decisions. By cataloging genetic variants that are common in different populations, researchers can create more accurate disease risk profiles and therapies designed for India’s genetic reality rather than relying on data from other regions.
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